Abstract G196 Table 1

Height, weight and BMI standard deviation scores (SDS) from diagnosis

	Whole group			Male subgroup			Female subgroup
	Mean (95% Cl)	N	p Value	Mean (95% Cl)	N	p Value	Mean (95% Cl)	N	p Value
Height SOS
Diagnosis	0.17 [0.O9 to 0.26]	77	–	0.17 [0.04 to 0.30]	37	–	0.18 [0.07 to 0.28]	40	–
1 year into treatment	−0.27 [−0.36 to−0.18]	69	<0.0001	−0.21 [−0.35 to−0.06]	32	0.03	−0.32 [−0.43 to−0.21]	37	<0.0O01
End–of–treatment (EoT)	−0.31 [−0.40 to−0.22]	68	<0.0001	−0.27 [−0.41 to−0.13]	32	<0.0001	−0.35 [−0.47 to −0.24]	36	<0.0001
1 year post–EoT(1YO)	−0.09 [−0.18 to O.00\|	66	<0.0001	−0.10 [−0.24 to 0.05]	31	<0.0001	−0.09 [−0.20 to 0.03]	35	0.005
2 years post–EoT (2YO)	−0.04 [−0.14 to O.06\|	58	<0.0001	−0.09 [−0.26 to 0.09]	23	<0.0001	−0.01 [−0.13 to O.10]	35	0.13
3 years post–EoT (3YO)	0.01 [−0.09 to 0.11]	53	O.004	−0.06 [−0.25 to 0.13]	20	0.006	0.05 [−0.07 to 0.17]	33	0.31
Weight SDS
Diagnosis	0.37 [0.26 to 0.48]	77	–	0.29 [0.12 to 0.46]	37	–	0.44 [0.30 to 0.59]	40	–
1 year into treatment	0.41 [0.30 to 0.52]	69	0.99	0.45 [0.27 to 0.62]	32	0.97	0.38 [0.24 to 0.53]	37	0.967
End–of–treatment (EoT)	0.74 [0.62 to 0.85]	68	<0.0001	0.62 [0.44 to 0.80]	32	0.003	0.85 [0.70 to 0.10]	36	0.003
1 year post–EoT (1YO)	0.83 [0.72 to 0.96]	66	<0.0001	0.72 (0.52 to 0.91]	31	<0.0001	0.96 [0.80 to 1.11]	35	<0.0001
2 years post–EoT (2YO)	0.83 [0.70 to 0.96]	58	<0.0001	0.61 [0.39 to 0.83]	23	<0.0001	1.00 [0.84 to 1.15]	35	<0.0001
3 years post–EoT (3YO)	0.78 [0.65 to 0.92]	53	<0.0001	0.55 [0.31 to 0.79]	20	<0.0001	0.95 [0.79 to 1.11]	33	<0.0001
BMI SDS
Diagnosis	0.35 [0.20 to 0.50]	77	–	0.24 [0.01 to 0.46]	37	–	0.46 [0.27 to 0.64]	40	–
1 year into treatment	0.81 [0.65 to 0.97]	69	<0.0001	0.87 [0.62 to 1.13]	32	0.001	0.77 [0.57 to 0.96]	37	0.13
End–of–treatment (EoT)	1.29 [1.13 to 1.45]	68	<0.0001	1.11 [0.85 to 1.36]	32	<0.0001	1.46 [1.26 to 1.66]	36	<0.0001
1 year post–EoT (1YO)	1.21 [1.05 to 1.37]	66	<0.0001	1.05 [0.79 to 1.31]	31	<0.0001	1.36 [1.15 to 1.56]	35	<0.0001
2 years post–EoT (2YO)	1.14 [0.96 to 1.31]	58	<0.0001	0.86 [0.56 to 1.17]	23	0.01	1.34 [1.14 to 1.55]	35	<O.0O01
3 years post–EoT (3YO)	1.04 [0.85 to 1.22]	53	<0.0001	0.77 [0.43 to 1.10]	20	0.02	1.24 [1.03 to 1.45]	33	<0.0001

Mean [95% confidence intervals; Cl] displayed for height–, weight– and EMI–SDS for the whole group and gender subgroups. Differences tested using a univariate model, incorporating time from diagnosis and anonymous subject identifier, with post–hoc analysis using Dunnett's two–sided test for multiple comparisons; p–Values ≤0.001 (versus diagnosis) are considered significant and displayed in italics. N = number or patients included in the analysis at the stated timepoint. YO =years out from end–of–treatment.