Percentage of participants having no understanding of clinical trial concepts: pretest versus post-test
| Children | Parents | |||
|---|---|---|---|---|
| TF | IP | TF | IP | |
| Clinical trial | ||||
| Pre | 46 (66.7) | 44 (67.7) | 22 (29.3) | 22 (30.1) |
| Post | 19 (27.5) | 14 (21.2) | 11 (14.7) | 5 (6.8) |
| Δ Pre-post | 39.2 | 46.5 | 14.6 | 23.3 |
| Randomisation | ||||
| Pre | 38 (55.1) | 27 (41.5) | 44 (58.7) | 33 (45.2) |
| Post | 23 (33.3) | 12 (18.2)* | 19 (25.3) | 11 (15.1) |
| Δ Pre-post | 21.8 | 23.3 | 33.4 | 30.1 |
| Placebo | ||||
| Pre | 61 (88.4) | 58 (89.2) | 24 (32.0) | 25 (34.2) |
| Post | 38 (55.1) | 6 (9.1)* | 10 (13.3) | 6 (8.2) |
| Δ Pre-post | 33.3 | 80.1 | 18.7 | 26.0 |
| Single blinding | ||||
| Pre | 67 (98.6) | 64 (98.5) | 49 (65.3) | 44 (61.1) |
| Post | 32 (46.4) | 12 (18.2)* | 11 (14.7) | 6 (8.2) |
| Δ Pre-post | 52.2 | 80.3 | 50.6 | 52.9 |
| Double blinding | ||||
| Pre | 67 (98.6) | 64 (98.5) | 56 (74.7) | 55 (75.3) |
| Post | 33 (47.8) | 9 (13.6)* | 11 (14.7) | 10 (13.7) |
| Δ Pre-post | 50.8 | 84.9 | 60.0 | 61.6 |
| Informed consent | ||||
| Pre | 27 (39.1) | 35 (53.8) | 9 (12.0) | 8 (11.0) |
| Post | 21 (30.4) | 28 (42.4) | 5 (6.7) | 3 (4.1) |
| Δ Pre-post | 8.7 | 11.4 | 5.3 | 6.9 |
Data are presented as n (%).
Δ=Pre-post change in understanding, *p<0.05 versus TF.
IP, interactive digital program; TF, traditional paper format.