Table 2

Comparison of the clinical characteristics of acute lymphoblastic leukaemia (ALL) children with and without joint involvement

Joint involvementNo joint involvement
n=53, % (median diagnostic delay)n=233, % (median diagnostic delay)p Value
Age, median4.4 years4.4 years
Non-articular pain73% (4 weeks)28% (4 weeks)0.01
 Leg pain45%18%<0.01
 Back pain28%8%<0.01
Constitutional symptoms, total55% (4 weeks)81% (3 weeks)<0.01
 Abdominal pain29%22%0.37
Signs of cytopenia, total61% (1 week)72% (1 week)0.10
 No signs24%8%<0.01
 No organomegaly44%29%0.05
Abnormal blood count76%92%<0.01
 Hb <10 g/dL59%80%<0.01
 Platelet count <100×109/L44%75%<0.01
 WBC >20×109/L17%36%<0.01
 WBC <4×109/L27%28%0.99
 ANC <1.0×109/L67%72%0.40
 Lymphoblasts in blood70%75%0.74
 LDH >500 IU/L63%70%0.33
 Uric acid >0.5 IU/L17%30%0.06
  • Bold type face is partly to highlight and partly to mark where there is value.

  • ANC, absolute neutrophil count; Hb, haemoglobin; LDH, lactate dehydrogenase; WBC, white blood cell count.