Table 3

Deaths aged less than 1 year

Reason for enrolment and relevant medical history	SUDI n=18	Cause of CONI PLUS death	Age at death in weeks
Group 1: SUDI in extended family Relationship to CONI PLUS baby
Aunt	Yes	SIDS	3
Aunt and cousin	Yes	Pneumonitis	3
Cousin	Yes	SIDS	8
Uncle	Yes	SIDS	28
Cousin	Yes	SIDS	31
Aunt	Yes	Unascertained	47
Group 2: Following ALTE Attributed cause for ALTE
Unexplained	Yes	SIDS associated with coronary artery myocardial bridge	8
Congenital anomaly		Hypertrophic cardiomyopathy (cleft palate and microcephaly contributing factors)	9
Congenital anomaly		Fibromuscular dysplasia	10
Congenital anomaly		Hypoplastic left heart	14
Infection		Tracheal stenosis with complete vascular ring	14
Unexplained	Yes	SIDS	16
Congenital anomaly		Parainfluenza 3 bronchiolitis, severe development delay	19
Convulsions	Yes	Unascertained	20
Unexplained	Yes	SIDS (intercurrent respiratory disease and unexplained recent and previous subdural haemorrhage)	22
Congenital anomaly	Yes	Cytomegalovirus pneumonitis, systemic cytomegalovirus infection and residual aortic coarctation	23
Congenital anomaly		Agenesis corpus callosum, bronchopneumonia	25
Congenital anomaly		Nemaline myopathy	41
Gastro-oesophageal reflux/feeding related		Spinal muscular atrophy type 1	42
Congenital anomaly		Asphyxiating thoracic-dystrophy—Jarcho–Levin	47
Group 3: Death in previous sibling with known cause Sibling cause of death
Myocarditis	Yes	Myocarditis	3 days
Congenital pneumonia		Ornithine transcarbamylase deficiency	3 days
Congenital myopathy		Mitochondrial myopathy	17
Prematurity in two siblings	Yes	Unascertained, Jeune syndrome, agenesis corpus callosum, left microphthalmia, rotavirus infection	25
Dandy–Walker syndrome		Dandy–Walker syndrome	28
Prematurity in two siblings		Spino-muscular atrophy	31
Prematurity	Yes	Unascertained	43
Group 4: Prematurity
28-week gestation, intrauterine growth restriction		Chronic lung disease	33
Group 6: Congenital anomaly/ill at birth
Treacher Collins syndrome	Yes	Aspiration pneumonia	4
Oesophageal atresia, tracheo-oesophageal fistula and duodenal atresia		Hypoxic ischaemic encephalopathy	13
Birth asphyxia	Yes	Hypoxic ischaemic encephalopathy	16
Pierre Robin sequence	Yes	Upper respiratory tract obstruction	18
Congenital contractures		Unspecified myopathy	25
Convulsions, neurodegenerative disorder		Epileptic encephalopathy	26
Cerebral palsy, global delay	Yes	H1N1 virus	34
Fallot's tetralogy		Renal failure complicating Fallot's repair	49
22q deletion and atrial septal defect		Respiratory cyncytial virus bronchiolitis, congenital anomalies	49

ALTE, apparent life threatening event; CONI PLUS, Care of Next Infant Plus; SIDS, sudden infant death syndrome; SUDI, sudden unexpected death in infancy.