Abstract PO-0934 Table 1
Route Tmax Cmax* AUC0-t* t1/2 CL Vss
hr mg/L hr*mg/L hr L/kr L
IV therapeutic0.93 (1.84)0.16 (0.06)0.54 (0.26)3.78 (3.09)2.72 (3.107.16
IV microdose0.47 (0.72)0.30 (0.19)0.84 (0.57)1.69 (0.88)1.76 (1.07)2.55
Oral therapeutic1.05 (0.74)0.14 (0.12)0.70 (0.79)2.62 (3.05)2.93 (2.08)8.36
Oral microdose0.65 (0.36)0.24 (0.1)0.90 (0.43)1.64 (1.02)1.46 (1.00)2.65
  • Data are mean and s.d. * Cmax and AUC0-t are dose normalised.