Table 3

Summary estimates: non-severe pneumonia

OutcomeSummary estimateNumber of studies (n=participants)Heterogeneity
Oral co-trimoxazole vs oral amoxicillin
 Clinical failureRR 1.09; 95% CI 0.93 to 1.273 (n=3759)χ2 p 0.007; I² 80%
 Cure rateRR 0.99; 95% CI 0.96 to 1.012 (n=3468)χ2 p 0.004; I² 88%
Oral levofloxocin vs oral co-amoxiclavulanic acid
 Cure rateRR 1.02; 95% CI 0.93 to 1.111 (n=3759)Not applicable
Oral azithromycin vs oral co-amoxiclavulanic acid
 Treatment failure (2 weeks)RR 1.20; 95% CI 0.45 to 3.212 (n=276)χ2 p 0.55; I² 0%
Amoxicillin vs co-amoxiclavulanic acid
 Cure rateOR 10.44; 95% CI 2.85 to 38.211 (n=100)Not applicable
Parenteral Ampicillin vs penicillin plus chloramphenicol
 Clinical cureRR 0.90; 95% CI 0.76 to 1.061 (n=101)Not applicable
 Treatment failureRR 1.88; 95% CI 0.69 to 5.121 (n=101)Not applicable