Table 4

Summary of ROC analysis in individual age groups

Optimum cut-off point for tTG (μ/mL)SensitivitySpecificityArea under ROC curve (95% CI)
All age groups<0.100.920.840.876 (0.841 to 0.911)
Age groups
 6–8 months<0.101.000.340.668 (0.469 to 0.868)
 9–11 months*NANANANA
 1–2 years<0.101.000.560.780 (0.690 to 0.871)
 3–5 years<0.100.920.760.832 (0.729 to 0.934)
 6–8 years<0.100.860.870.835 (0.704 to 0.966)
 9–11 years<0.100.830.900.857 (0.734 to 0.980)
 12–17 years<0.100.940.940.949 (0.917 to 0.980)
  • *No patients aged 9–11 months with absent IgA identified.

  • IgA, immunoglobulin A; ROC, receiver operating characteristic; tTG, tissue transglutaminase.