Added value of the ‘clinical eye’ or faecal calprotectin testing in a population of children and teenagers suspected of having inflammatory bowel disease
| Characteristics | ‘Clinical eye’ of the paediatrician | Faecal calprotectin | Faecal calprotectin (gastrointestinal infections excluded) |
|---|---|---|---|
| N | 117 | 117 | 104 |
| True positives | 42 | 42 | 42 |
| True negatives | 49 | 55 | 50 |
| False positives | 26 | 20 | 12 |
| False negatives | 0 | 0 | 0 |
| Pretest probability (%) | 36 | 36 | 40 |
| Sensitivity (% (95% CI)) | 100 (92 to 100) | 100% (92 to 100) | 100 (92 to 100) |
| Specificity (% (95% CI)) | 65 (53 to 76) | 73% (62 to 83) | 81 (69 to 90) |
| Positive likelihood ratio (95% CI) | 2.9 (2.1 to 3.9) | 3.8 (2.6 to 5.5) | 5.2 (3.1 to 8.6) |
| Negative likelihood ratio (95% CI) | 0 | 0 | 0 |
| Post-test probability given a positive test result (% (95% CI)) | 62 (49 to 73) | 68 (55 to 79) | 78 (64 to 88) |
| Post-test probability given a negative test result (% (95% CI)) | 100 (93 to 100) | 100 (93 to 100) | 100 (93 to 100) |