Table 3

Differential diagnosis of this FAS series made on genetic testing

22q11dup22q11del14q21.1dup/16p13.3dup2p16.1p15del22q11dup1q21dup15q13.3del
Age seen (years)8.259.921.21115.836.71.4
Birth weight (centile)0.4nk75400.42525
Weight at referral (centile)25275250.4759
Height at referral (centile)9275250.47525
OFC at referral (centile)0.4250250.420.4
Care orderAdopted+++Adopted++
Family historyLDLDLDOtherLD
History of alcohol exposureProbableDefiniteProbableProbableProbableProbableDefinite
Abnormal prenatal scannknknknk+No care
Speech delay+nk+++
Microcephaly+++++
Growth failure++++
Intellectual disability+++++++
Behaviour problems+++++++
Pathogenic++++++
  • FAS, fetal alcohol syndrome; LD, learning difficulties; OFC, occipital-frontal circumference; nk, not known; +, present; -, absent..