Outcome | Full | Shared | Hybrid | p Value |
---|---|---|---|---|
Number | 77 | 102 | 20 | |
Mean age (years) | 9.3 (5.7) | 9.3 (5.4) | 10.5 (4.8) | |
Male | 47 | 54 | 11 | |
Female | 30 | 48 | 9 | |
Pancreatic sufficient | 9 | 4 | 1 | |
Genetics | ||||
dF508/dF508 | 44% | 49% | 40% | |
dF508/other | 39% | 41% | 40% | |
Other/other | 17% | 10% | 10% | |
Nutrition | ||||
Weight (kg) | 32.1 (19.8) | 30.3 (16.1) | 35.3 (17.6) | 0.5 |
Height (cm) | 126 (35.0) | 129 (27.9) | 136 (24.6) | 0.5 |
BMI (kg/m2)* | 17.1 (4.1) | 17.0 (2.9) | 18.1 (2.8) | 0.4 |
Weight SDS | −0.59 (1.34) | −0.64 (1.45) | −0.27 (1.32) | 0.6 |
Height SDS | −0.96 (1.44) | −1.0 (1.50) | −0.78 (1.37) | 0.8 |
BMI SDS | 0.06 (1.0) | 0.04 (1.0) | 0.26 (1.2) | 0.7 |
Infection | ||||
Airway cultures/year | 7.07 (3.1) | 7.0 (3.0) | 7.01 (2.4) | |
Chronic PA | 2 (2.6%) | 9 (8.8%) | 1 (5%) | 0.2 |
Chronic therapies | ||||
Tube fed | 6 (7.8%) | 3 (2.9%) | 0 (0%) | 0.2 |
Macrolide | 36 (47%) | 45 (44%) | 12 (60%) | 0.4 |
Nebulised antibiotics | 39 (51%) | 48 (47%) | 11 (55%) | 0.7 |
Nebulised DNAse | 42 (55%) | 58 (57%) | 13 (65%) | 0.7 |
Data presented as mean and SD except
↵* where median and IQR presented.
BMI, body mass index; PA, Pseudomonas aeruginosa; SDS, SD score.