Group results of patients positive PCR for EV and HPeV in CSF
| Clinical presentation percentage of patients with presence of sign or symptom | Age and laboratory results median (range) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Group | Fever (≥38.5°C) | Irritability | Meningism | Convulsion | GI symptoms | Respiratory symptoms | Age, years | Maximal CRP, mg/l | Blood leukocyte count, ×109 cells/l | CSF leucocytes/µl |
| Enterovirus positive in CSF (n=12) | 83% | 42% | 8% | 25% | 25% | 25% | 0.1 (0–4.6) | 11 (0–70) | 9.5* (7–27) | 16 (0–294) |
| Human parechovirus positive in CSF (n=10) | 80% | 90% | 20% | 0% | 50% | 20% | 0.1 (0.1–0.3) | 5 (0–115) | 6.2* (4–21) | 2 (1–15) |
Meningism: neck stiffness and/or increased discomfort upon anteflexion in the hips. Respiratory symptoms: tachypnoea, dyspnoea, cough or auscultatory abnormalities
↵* p<0.05 between EV and HPeV groups.
CRP, C-reactive protein; CSF, cerebrospinal fluid; EV, enterovirus; GI, gastrointestinal (reduced feeding, vomiting or diarrhoea); HpeV, human parechovirus.