A | At least one meta-analysis, systematic review or randomised controlled trial rated as 1++ and directly applicable to the target population; or |
A body of evidence consisting principally of studies rated as 1+, directly applicable to the target population and demonstrating overall consistency of results |
B | A body of evidence including studies rated as 2++, directly applicable to the target population, and demonstrating overall consistency of results; or |
Extrapolated evidence from studies rated as 1++ or 1+ |
C | A body of evidence including studies rated as 2+, directly applicable to the target population and demonstrating overall consistency of results; or |
Extrapolated evidence from studies rated as 2++ |
D | Evidence level 3 or 4; or |
Extrapolated evidence from studies rated as 2+ |
Good practice point | Recommended best practice based on the clinical experience of the pathway working group |
Clinical practice guideline | Evidence included from recommendations listed in appraised clinical guidelines, position papers and expert consensus statements |