Screened (n=41) | Non-screened (n=38) | p value | |
---|---|---|---|
Sex Male:Female | 15:26 | 17:21 | 0.5 |
Meconium ileus (%) | 8 (19) | 5 (13) | 0.6 |
Gestational age, weeks (SD) | 38.9 (1.8) | 39.2 (1.7) | 0.5 |
Birth weight, gr (SD) | 3302 (672) | 3233 (675) | 0.7 |
Age at diagnosis (months) | |||
Mean (range) | 4.1 (0.03–80) | 7.1 (0.03–38) | 0.3 |
Excluding MI | 4.8 (0.46–80) | 8.3 (1.12–38) | 0.3 |
Excluding two patients missed by NBS (n=39 vs 38) | 1.6 (0.03–3.7) | 7.1 (0.03–38) | 0.001* |
Age at last measurement before transfer (SD) | 17.5 (0.98) | 17.4 (0.77) | 0.9 |
Pancreatic sufficient (%) | 4 (10) | 2 (5) | 0.7 |
Deaths due to CF from original cohort at transfer to adult care (%) | 7 (17) | 9 (23) | 0.24 |
Total lost to follow-up from original cohort (including death) at transfer to adult care (%) | 19 (32) | 19 (33) | 0.5 |
↵* p≤0.001 for difference between screened and non-screened; analysis of variance.
CF, cystic fibrosis; MI, meconium ileus; NBS, newborn screening.