Table 4

Summary of reported musculoskeletal events from 32 studies

Musculoskeletal eventsFrequency (%)
Arthralgia130 (50.0)
Tendon or joint disorder48 (19.0)
Reduced movement/stiffness39 (15.0)
Joint swelling8 (3.0)
Radiological confirmed arthropathy6 (2.3)
Myalgia4 (1.6)
Arthritis3 (1.2)
Pain in extremity1 (0.4)
Osteitis1 (0.4)
Unknown18 (7.0)
Total258* (100)
  • * 258 musculoskeletal events occurred in 232 patients.