Summary statistics for Cmax, AUC0−t and AUC0−∞
| Cmax (ng/ml) | AUC0−t (ng/ml·h) | AUC0−∞ (ng/ml·h) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Formulation | Solution | Suspension | Tablet | Solution | Suspension | Tablet | Solution | Suspension | Tablet |
| N | 18 | 17 | 18 | 18 | 17 | 18 | 18 | 17 | 18 |
| Mean | 362.4 | 387.1 | 486.5 | 1232.1 | 1184.0 | 1492.5 | 1515.3 | 1411.7 | 1672.6 |
| SD | 247.0 | 313.0 | 294.3 | 889.2 | 768.9 | 970.7 | 1234.0 | 899.1 | 1119.3 |
| Minimum | 75.3 | 57.3 | 70.9 | 222.6 | 243.7 | 383.6 | 232.5 | 337.1 | 434.0 |
| Maximum | 800.0 | 1095.3 | 1007.8 | 3253.1 | 2693.7 | 3517.2 | 4617.3 | 3427.4 | 4327.8 |
AUC0−t, area under the concentration versus time curve from time 0 to the last quantifiable time point; AUC0−∞, area under the concentration versus time curve from time 0 extrapolated to time infinity; Cmax, maximum plasma concentration.