Causes of chest pain by site of origin
| Cardiac | Structural lesions |
| Acquired/inflammatory conditions (eg, vasculitis, cardiomyopathy) | |
| Arrhythmias | |
| Respiratory | Infection |
| Pleural disease | |
| Asthma | |
| Foreign body | |
| Pneumothorax, pneumomediastinum | |
| Inhalant irritation | |
| Dysfunctional breathing | |
| Thoracic malignancy | |
| Gastrointestinal | Gastro-oesophageal reflux |
| Oesophagitis (reflux, eosinophilic) | |
| Gastritis | |
| Oesophageal spasm | |
| Achalasia | |
| Oesophageal foreign body | |
| Pancreatitis | |
| Subdiaphragmatic abscess | |
| Musculoskeletal | Slipping rib syndrome |
| Tietze's syndrome | |
| Costochondritis | |
| Vertebral deformities or collapse | |
| Myofascial trauma or strain | |
| Miscellaneous | Precordial catch syndrome |
| Stitch | |
| Breast development | |
| Herpes zoster |