Effects of DHA supplementation
| Change vs baseline using placebo as comparator | ||
|---|---|---|
| DHA | ||
| 250 mg | 500 mg | |
| DHA (%) | 0.65*** (0.30 to 1.01) | 1.15***,† (0.87 to 1.43) |
| ISI | 1.2** (0.4 to 1.9) | 1.2** (0.7 to 1.8) |
| ALT (U/l) | −10 (−23 to 2) | −1 (−14 to 13) |
| Triglycerides (mg/dl) | −14* (−27 to −2) | −16* (−29 to −3) |
| BMI (SDS) | 0.03 (−0.07 to 0.13) | −0.11 (−0.35 to 0.13) |
Values are regression coefficients (effect size) and 95% robust CI (effect variability, given in brackets).
↵* p < 0.05,
↵** p < 0.01 and
↵*** p < 0.001 vs placebo.
↵† p = 0.002 vs DHA 250 mg.
ALT, alanine transaminase; BMI, body mass index; DHA, docosahexaenoic acid; ISI, insulin sensitivity index; SDS, standard deviation score.