Table 3

Differences in neuro-developmental outcomes between extremely preterm children with true negative and false positive SCQ screens using a total SCQ cut-off score of ≥14

SCQ screen n (%)
OutcomeTrue negative (n=140)False positive (n=22)OR (95% CI)p Value
Functional impairment
 Neuromotor impairment, n (%)7 (5.0%)4 (18.2%)4.22 (1.12 to 15.86)0.045
 Visual impairment, n (%)6 (4.3%)4 (18.2%)4.96 (1.28 to 19.29)0.031
 Hearing impairment, n (%)1 (0.7%)1 (4.5%)6.62 (0.40 to 109.89)0.254
 Cognitive impairment, n (%)41 (29.3%)15 (68.2%)5.17 (2.00 to 113.62)0.001
 MPC (IQ) scores, mean (SD)89.14 (14.26)69.68 (19.36)−19.46 (−28.32 to −10.59)*0.000
 Overall functional disability, n (%)48 (34.3%)15 (68.2%)4.11 (1.57 to 10.76)0.004
Parent SDQ: clinical range
 Total difficulties, n (%)35 (25.0%)16 (72.7%)8.00 (2.90 to 22.04)0.000
 Emotional symptoms, n (%)21 (15.0%)11 (50.0%)5.67 (2.18 to 14.74)0.001
 Conduct problems, n (%)12 (8.6%)6 (27.3%)4.0 (1.32 to 12.13)0.020
 Hyperactivity/inattention, n (%)28 (20.0%)16 (72.75)10.67 (3.83 to 29.75)0.000
 Peer problems, n (%)30 (21.4%)13 (59.1%)5.30 (2.07 to 13.57)0.001
  • * Mean difference (95% CI).

  • Behavioural outcomes were assessed using the Strengths and Difficulties Questionnaire (SDQ) completed by parents (n=162). Children with scores >90th percentile of a comparison group of 153 classmates were classified as at risk for clinically significant difficulties in each domain and overall for total difficulties.

  • MPC, Mental Processing Composite scores from the Kaufman Assessment Battery for Children; SCQ, Social Communication Questionnaire; SDQ, Strengths and Difficulties Questionnaire.