Clinical presentation of the patients
| All patients (n=22) | Non-BRICHOS domain (n=16) | BRICHOS domain (n=6) | p Value | |
|---|---|---|---|---|
| Patients, n | 22 | 16 | 6 | |
| Sex male/female | 10 (45)/12 (55) | 6 (27)/10 (45) | 4 (18)/2 (9) | |
| Median age at onset (range) in months | 3 (0–24) | 4 (2–24) | 2 (0–2) | 0.004 |
| Neonatal respiratory distress | 4 (18) | 0 (0) | 4 (18) | 0.008 |
| Acute bronchiolitis at onset | 9 (41) | 6 (27) | 3 (14) | |
| Respiratory syncitial virus infection | 5 (23) | 4 (18) | 1 (5) | |
| Gastro-oesophageal reflux | 8 (36) | 5 (23) | 3 (14) | |
| Failure to thrive | 22 (100) | 16 (73) | 6 (27) | |
| Physical findings | ||||
| Tachypnoea/dyspnoea | 22 (100) | 16 (73) | 6 (27) | |
| Clubbing | 1 (5) | 1 (5) | 0 (0) | |
| Crackles | 5 (23) | 5 (23) | 0 (0) | |
The percentage of the total is indicated in parentheses.