Table 1

Main parameters in children with initially abnormal levels in groups 1 and 2 (medians)

Start MMF3 months after starting MMF6 months after starting MMF12 months after starting MMF
ParametersGroup 1Group 2Group 1Group 2Group 1Group 2Group 1Group 2
Serum C3 (g/l)0.530.630.990.821.060.871.15*1.2*
Serum C4 (g/l)*0.11
Urine albumin/creatinine ratio (mg/mmol)190.036.769.195.615.1*3.45.1*28.1
Haemoglobin (g/dl)9.79.511.713.511.413.112.6*13.1*
ESR (mm in the first hour)*19.016.0*13.5*
Lymphocytes × 1090.50.831.011.60.941.41.7*1.8*
ANA (IU/ml)1:25601:12801:25601:12801:1601:1601:1601:160
Anti-dsDNA (IU/ml)273655.725.520.8112510
Serum creatinine (µmol/l)100969652724153*44
Prednisolone dose (mg/day)*7.56.5*5.0*
  • * p<0.05; 3, 6 and 12 months compared to the onset of therapy.

  • ANA, antinuclear antibody; ESR, erythrocyte sedimentation rate; MMF, mycophenolate mofetil.