Table 1 Characteristics of the study population (12–18 years old) by antiepileptic drug
CarbamazepineLamotrigineSodium valproateTotal study antiepileptic drugs
Prescriptions (%)50 779 (34.5)39 516 (26.9)56 816 (38.6)147 111 (100.0)
Number of prescriptions for controlled release formulations (%)21 550 (42.4)16 926 (29.8)
Median number of prescriptions (IQR)12 (4–29)17 (6–38)13 (5–27)16 (6–36)
Subjects* (%)2451 (45.2)1418 (26.2)2833 (52.3)5417 (100.0)
    Male/female1323/1128556/8621558/12752836/2581
    Number of female subjects treated with monotherapy (%)
        1993–2006653 (39.1)298 (17.8)721 (43.1)1672 (100.0)
        1993100 (50.0)1 (0.5)99 (49.5)200 (100.0)
        2006109 (30.4)123 (34.4)126 (35.2)358 (100.0)
    Number of female subjects treated with monotherapy79 (12.1)49 (16.4)105 (14.6)233 (13.9)
    and co-prescribed oral contraceptive medication (%)
    Number of female subjects treated with monotherapy14 (2.1)6 (2.0)13 (1.8)33 (2.0)
    and having a pregnancy clinical code (%)
  • IQR, inter-quartile range.

  • *Subjects were counted more than once if prescribed more than one antiepileptic drug.