Reporting of adverse effects in 107 articles studied
| Item | Number (%) |
|---|---|
| Adverse effects mentioned in article | 83 (78) |
| Adverse effects mentioned in methods section | 49 (46) |
| Standardised method for adverse effects | 36 (34) |
| Categorisation of adverse effects | 10 (9) |
| Adverse effects mentioned in result section | 81 (76) |
| Number of adverse effects given | 69 (64) |
| Individuals with adverse effects given | 28 (26) |
| Table with adverse effects | 33 (31) |
| Number of withdrawals | 27 (25) |
| Adverse effects per study arm | 69 (65) |
| Total children studied | 24 056 |
| (Per study mean; median; minimum; maximum) | 224; 70; 10; 4906 |
| Total adverse effects found | 7246 |
| (Per study mean; median; minimum; maximum) | 105; 30; 0; 2343 |
| Total fatalities | 22 |
| Total severe adverse events | 338 |
| (Per study mean; median; minimum; maximum) | 6; 0; 0; 91 |
| Duration of study (in weeks) (per study mean; median; minimum; maximum) | 12; 4; 1; 150 |
| Ioannidis score* | |
| (Mean; median; minimum; maximum) | 2; 2; 0; 5 |
| Consort score* | |
| (Mean; median; minimum; maximum) | 3; 3; 1; 9 |
↵* For construction of these scores: see text.