Table 4

Change over 1 year

Outcome (median change (IQR))n*Without NHn*NH
Pulmonary function tests (% predicted)
 FVC231.0 (−2.0 to 8.0)4−5.0 (−18.8 to 2.8)
 FEV230.0 (−3.0 to 7.0)4−6.5 (−22.0 to 3.0)
 RV/TLC20−0.03 (−0.068 to 0.028)40.075 (−0.003 to 0.168)
 MIP203.5 (−11.3 to 19.8)4−2.0 (−8.5 to 13.5)
 MEP202.5 (−18.8 to 18.8)42.5 (−7.5 to 38.8)
Manual muscle strength (/10)240.5 (−0.1 to 0.9)4−0.7 (−1.0 to 0.0)
Child Health Questionnaire
 Global health250.0 (0.0 to 25.0)50.0 (−15.0 to 27.5)
 Physical functioning250.0 (0.0 to 16.7)5−5.6 (−22.2 to 5.6)
 Role/social limitations – emotional/behavioural250.0 (0.0 to 0.0)50.0 (0.0 to 22.2)
 Role/social limitations – physical240.0 (0.0 to 12.5)516.7 (8.3 to 33.3)
 Bodily pain/discomfort240.0 (−10.0 to 20.0)5−20.0 (−25.0 to 5.0)
 Behaviour244.2 (−5.8 to 6.7)54.2 (2.1 to 11.3)
 Global behaviour item250.0 (−7.5 to 7.5)50.0 (0.0 to 20.0)
 Mental health250.0 (−7.5 to 10.0)55.0 (−2.5 to 15.0)
 Self-esteem250.0 (−12.5 to 8.3)5−8.3 (−14.6 to 16.7)
 General health perceptions248.3 (−5.4 to 16.7)5−12.5 (−17.1 to 0.4)
 Change in health250.0 (0.0 to 1.0)50.0 (0.0 to 1.5)
 Parental impact – emotional250.0 (−16.7 to 33.3)58.3 (0.0 to 12.5)
 Parental impact – time250.0 (−5.6 to 11.1)511.1 (−50.0 to 22.2)
 Family activities250.0 (−4.2 to 4.2)58.3 (−4.2 to 33.3)
 Family cohesion250.0 (0.0 to 0.0)525.0 (−27.5 to 50.0)
Conners (parent questionnaire – raw scores)
 Inattentive231.0 (−4.0 to 5.0)4−2.0 (−2.0 to 8.5)
 DSM inattentive231.0 (−3.0 to 3.0)4−1.0 (−2.5 to 5.0)
 Global index230.0 (−2.0 to 0.0)4−1.5 (−3.0 to 3.8)
  • * The total number of participants for whom information was available at 1 year of follow-up. The ranges in brackets refer to median and interquartile ranges.

  • DSM, Diagnostic and Statistical Manual of Mental Disorders; FEV, forced expiratory volume; FVC, forced vital capacity; MEP, maximal expiratory pressure; MIP, maximal inspiratory pressure; NH, nocturnal hypoventilation; RV, residual volume; TLC, total lung capacity.