Clinical predictors
| Factors, n (%) | NH* | Without NH* | OR (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | NPV (95% CI) | PPV (95% CI) |
|---|---|---|---|---|---|---|---|
| Scoliosis | 6/7 (85.7) | 9/38 (23.7) | 0.05 (0.01 to 0.49) | 85.7 (48.7 to 97.4) | 76.3 (60.8 to 87.0) | 96.7 (83.3 to 99.4) | 40.0 (19.8 to 64.3) |
| Manual muscle strength mean score <5 | 3/7 (42.9) | 6/38 (15.9) | 0.25 (0.04 to 1.41) | 42.9 (15.8 to 75.0) | 84.2 (69.6 to 92.6) | 88.9 (74.7 to 95.6) | 33.3 (12.1 to 64.6) |
| Pulmonary function testing ≤50% | |||||||
| FVC | 4/7 (57.1) | 3/37 (8.1) | 0.09 (0.02 to 0.56) | 57.1 (25.0 to 84.2) | 91.9 (78.7 to 97.2) | 91.9 (78.7 to 97.2) | 57.1 (25.0 to 84.2) |
| FEV1 | 3/7 (42.9) | 3/37 (8.1) | 0.12 (0.02 to 0.79) | 42.9 (15.8 to 75.0) | 91.9 (78.7 to 97.2) | 89.5 (75.9 to 95.8) | 50.0 (18.8 to 81.2) |
| MIP | 2/7 (28.6) | 9/33 (27.3) | 0.94 (0.15 to 5.73) | 28.6 (8.2 to 64.1) | 72.7 (55.8 to 84.9) | 82.8 (65.5 to 92.4) | 18.2 (5.1 to 47.7) |
| MEP | 3/7 (42.9) | 6/32 (18.8) | 0.31 (0.05 to 1.75) | 42.9 (15.8 to 75.0) | 81.3 (64.7 to 91.1) | 86.7 (70.3 to 94.7) | 33.3 (12.1 to 64.6) |
| BMI percentiles ≥95th | 2/7 (28.6) | 13/38 (34.2) | 0.77 (0.13 to 4.52) | 22.2 (6.3 to 54.7) | 65.8 (49.9 to 78.8) | 78.1 (61.2 to 89.0) | 13.3 (3.7 to 97.9) |
↵* The total number of participants for whom information was available varies due to missing data.
BMI, body mass index; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; MEP, maximal expiratory pressure; MIP, maximal inspiratory pressure; NH, nocturnal hypoventilation; PPV, positive pressure ventilation.