Methods based on clinical features |
Symptom based |
Age at onset |
Natural history |
Severity |
Defined by triggers |
Allergic versus non-allergic |
Exercise induced |
Viral-triggered versus multi-triggered wheeze |
Response to treatment |
Corticosteroid responsive |
Methods based on pathophysiological features |
Pathological tests (biopsy, induced sputum & bronchoalveolar lavage) |
Eosinophilic |
Neutrophilic |
Non-invasive markers of airway inflammation |
Exhaled nitric oxide |
Exhaled breath condensate |
Pulmonary function tests |
Fixed versus bronchodilator-reversible airway obstruction |
Bronchial responsiveness to exercise, cold air, chemical challenge |