Comparison of the final diagnosis of the children with fever without source in the validation and in the derivation population
| Validation population (n=406) | Derivation population(n=202) | p | |
|---|---|---|---|
| Male | 203 (50) | 112 (55) | NS |
| Age* (month) | 9.6 (0.2–36) | 9 (0.3–35) | NS |
| Duration of fever | p<0.001 | ||
| <8 h | 45 (11) | 28 (14) | |
| 8–24 h | 98 (24) | 80 (40) | |
| >24 h | 263 (65) | 91 (46) | |
| SBI | 92 (22.7) | 54 (26.7) | NS |
| Pyelonephritis | 50 (12.3) | 42 (20.8) | |
| Pneumonia | 24 (5.9) | 6 (3) | |
| Occult bacteremia† | 6 (1.5) | 3 (1.5) | |
| Meningitis | 7 (1.7) | 0 | |
| Sepsis | 3 (0.7) | 0 | |
| Septic arthritis | 2 (0.5) | 1 (0.5) | |
| Others | 0 | 2 (1) | |
| Focal bacterial infection | 64 (15.8) | 26 (12.8) | NS |
| Probable viral infection | 250 (61.6) | 122 (60.4) | NS |
Data are number (%) of patients, unless otherwise indicated.
↵* Median (range).
† Positive blood cultures were also found in patients with meningitis (five), pyelonephritis (four) and pneumonia (two) for the validation set and pyelonephritis (two), pneumonia (one) and osteoarthritis (one) for the derivation set.