Table 3 Prognostic factors for treatment failure among children admitted with severe pneumonia who had S pneumoniae isolated and were treated with penicillin/ampicillin
VariablesSuccessFailureUnadjustedAdjustedP*
n = 187(79%)n = 49(21%)RR (95% CI)RR (95% CI)
Susceptibility0.92
Susceptible942511
Intermediate49141.05 (0.57–1.76)1.14 (0.58–1.97)
Resistant44100.88 (0.44–1.60)1.03 (0.49–1.90)
Age (months)1.01 (0.99–1.02)1.00 (0.98–1.02)0.84
Pleural effusion on admission90352.21 (1.30–3.41)2.31 (1.33–3.61)0.003
Lethargy on admission50211.75 (1.06–2.63)1.84 (1.10–2.79)0.02
Previous antibiotic use4290.82 (0.41–1.49)0.77 (0.35–1.46)0.44
  • *Log likelihood ratio test.

  • RR, relative risk.