Guideline outcomes under Newcastle guidelines (actual outcome) | Newcastle | Predicted guideline outcomes under NICE | ||||||||
Mantoux | Total | Mantoux negative (77) | Mantoux positive (26) | Total | ||||||
Negative | Positive | QFG positive | QFG negative | QFG not suggested by NICE | QFG positive | QFG negative | QFG not suggested by NICE | |||
Number = 103 | 77 | 26 | 103 | 1 | 25 | 51** | 4 | 21 | 1 | 103 |
Treatment for TB disease | 1[1] | 4[4] | 5[5] | 0 | 0 | 0 | 3 | 0 | 0 | 3 |
Treatment for LTBI | 0[0] | 22[20] | 22[20] | 1 | 0 | 0 | 1 | 0 | 1†† | 3 |
BCG | 24[22*] | 0 | 24[22] | 0 | 7 | 17 | 0 | 0 | 0 | 24 |
Advice | 52[52] | 02 | 52[54] | 0 | 18 | 34*** | 0 | 21† | 0 | 73 |
*Lost to follow-up.
**Includes one child who tested QFG positive.
***Includes one child not tested in the algorithm (QFG normal), with abnormal CXR/pulmonary TB.
†Includes one child with abnormal CXR not given CXR/clinical exam under NICE as they were QFG negative, but actually treated for TB.
††QFG not done as child <2 years old with positive Mantoux.