Table 2 Chronological changes in GH prescribing patterns, compliance and growth responses from 1999 to 2003
1999,n = 352001,n = 302003,n = 49p Trend
Age (years)11.013.513.7*0.049
Years on GH therapy2.
Given choice of GH device53%53%68%*0.3
Prescription duration (weeks)457*0.02
>2 injections missed/week36%17%8%**0.003
Height velocity (cm/year)†*0.03
Height velocity (SDS/year)†**0.005
  • *p<0.05, **p<0.005 for 2003 vs 1999.

  • †Adjusted for age and duration of GH therapy.

  • Data are medians or % (n) of each year group.