Table 1 Audit criteria for assessment of possible SCID
Clinical record of features of SCID (absent/present and number of episodes and age at episode)
    1. Failure to thrive
    2. Diarrhoea
    3. Respiratory infections
    4. Candida infection
    5. Skin rashes
    6. Lymphadenopathy
    7. Hepatomegaly and/or splenomegaly
    8. Haematological abnormalities
    9. Autoimmune manifestations
    10. “BCG osis”
    11. Severe viral infection
    12. Fever of unknown origin
    13. Nausea and vomiting
    14. Septicaemia
Risk factors/associated congenital abnormalities (absent/present/unknown and relevant details)
    15. Consanguinity
    16. Family history of early deaths
    17. High risk ethnicity
    18. Congenital cardiac disorder
    19. Skeletal abnormalities
Evidence of consideration of lymphopenia and SCID (absent/present)
    20. Other lymphocyte counts
    21. Acknowledgement of lymphopenia in notes/letters
    22. SCID recorded as a differential diagnosis
    23. Evidence of lymphocyte subsets analysis request
    24. SCID diagnosis