Table 2 Respiratory health and growth at 62–87 months of age for extremely preterm children (with and without moderate or severe BPD) and comparison term children
BPD36w (n = 163)No BPD (n = 56)BPD vs no BPDComparison group (n = 148)No BPD vs comparison group
n%n%OR (95% CI)n%OR (95% CI)
Height (cm), mean (quartiles)111 (109; 117)113 (109; 117)121 (111; 122)
Height SD score, mean (quartiles)−0.98 (−1.61; −0.31)−0.87 (−1.68; −0.27)0.0 (−0.89; 0.56)
Weight (kg), mean (quartiles)18.7 (16.5; 20.5)18.7 (17.1; 20.0)21.6 (18.5; 23.5)
Weight SD score, mean (quartiles)−1.22 (−2.10; −0.37)−1.15 (−1.75; −0.38)0.07 (−0.71; 0.73)
Wheezed in past year5936.21119.62.3 (1.1 to 4.8)*1912.81.7 (0.73 to 3.8)
Had episodes in past year571019
Number of episodes in past year
        1–32950.9770.0p = 0.35†1263.2p = 0.89†
        4–122035.1220.0736.8
        >12814.0110.00
Severe episodes1811.023.63.3 (0.75 to 14.9)21.42.7 (0.37 to 19.7)
Wheeze or cough at night5131.3916.12.3 (1.1 to 5.0)*1610.81.6 (0.66 to 3.8)
Wheeze on exercise4225.9916.11.8 (0.82 to 4.0)1711.61.5 (0.61 to 3.5)
Inhaled medications
    Bronchodilators last 12 months4927.8916.12.2 (1.0 to 4.8)*1811.31.4 (0.59 to 3.3)
    Steroids last 12 months4223.9711.72.4 (1.0 to 5.6)*159.41.3 (0.49 to 3.3)
    Bronchodilators currently2614.835.03.3 (0.96 to 11.3)116.90.71 (0.19 to 2.6)
    Steroids currently3117.646.73.0 (1.0 to 8.9)*116.90.97 (0.30 to 3.2)
Current paediatrician surveillance3219.858.92.5 (0.93 to 6.8)64.12.3 (0.67 to 7.9)
Ever diagnosed as “asthma”7144.12035.71.4 (0.76 to 2.7)3221.92.0 (1.0 to 3.9)
n = 134n = 53Difference in means (95% CI)n = 142Difference in means (95% CI)
Peak expiratory flow (l/min), mean (SD)133(37)154(44)20 (7 to 33)‡182(42)29 (15–42)‡
p = 0.003p = 0.002
  • *Significant odds ratios; †χ2 for trend; ‡t test.

  • Forms were returned for 219 extremely preterm and 148 comparison children; BPD defined as oxygen use at 36 weeks postmenstrual age. BPD, bronchopulmonary dysplasia; OR, odds ratio.