Table 1 Frequency of case definition criteria, as cited for the 112 confirmed cases, with population rates, median age (interquartile range) and median length of stay (interquartile range)
Clinical descriptionFrequencyRate (100 000/year)(95% CI)Median age(IQR), yearsMedian length of stay(IQR), days
Pneumonia (abnormal x ray)300.22 (0.15 to 0.31)3.0 (1.0–5.0)8.0 (5.0–14.75)
Bacteraemia/septic shock300.22 (0.15 to 0.31)1.5 (1.0–3.0)9.0 (5.0–14.0)
Encephalitis260.19 (0.12 to 0.28)4.0 (2.0–5.25)7.5 (2.75–13.25)
Ataxia250.18 (0.12 to 0.27)3.0 (2.0–5.0)6.0 (1.5–9.0)
Toxic shock syndrome/toxin-mediated disease140.10 (0.06 to 0.17)3.0 (2.0–4.0)6.5 (5.75–10.00)
Necrotising fasciitis70.05 (0.02 to 0.11)1.0 (1.0–4.0)9.5 (6.75–15.25)
Purpura fulminans/disseminated coagulopathy50.04 (0.02 to 0.09)4.0 (2.0–7.0)9.0 (1.0–23.75)
Fulminant varicella50.04 (0.02 to 0.09)5.0 (4.0–8.5)8.0 (2.5–20.0)
Neonatal varicella (perinatal infection)30.02 (0.007 to 0.07) or0 (0–0)2.0 (2.0–4.0)
0.37* (0.12 to 1.13)
Reye’s syndrome00NANA
Admitted to ICU/HDU290.21 (0.15 to 0.31)2.0 (1.0–4.0)12 (6.0–26.0)
Death60.04 (0.02 to 0.10)4.5 (1.5–11.0)2.0 (1.0–2.5)
  • *The figures for neonatal varicella are additionally calculated using live births in 2003 as the denominator (n = 757 109).

  • The denominator for calculation of population rates is the combined estimated mid-year 2003 population estimate for those aged <16 years in England, Wales, Scotland, Northern Ireland and Ireland (n = 12 605 861).