Any wheeze at 4 years, n = 454 (16%) | Transient wheeze, n = 222 (8%) | Late-onset wheeze, n = 169 (6%) | Persistent wheeze, n = 284 (10%) | |||||||||
n | Crude OR(95% CI) | Adjusted OR(95% CI) | n | Crude OR(95% CI) | Adjusted OR(95% CI) | n | Crude OR(95% CI) | Adjusted OR(95% CI) | n | Crude OR(95% CI) | Adjusted OR(95% CI) | |
Birth weight ⩽10th percentile, n = 288 | 65 | 1.65 (1.22 to 2.23) | 1.39 (0.90 to 2.12) | 28 | 1.50 (0.98 to 2.30) | 1.24 (0.66 to 2.34) | 23 | 1.57 (0.98 to 2.50) | 1.35 (0.71 to 2.56) | 42 | 1.82 (1.27 to 2.62) | 1.47 (0.87 to 2.49) |
Birth weight ⩾90th percentile, n = 292 | 46 | 1.06 (0.75 to 1.49) | 1.19 (0.80 to 1.75) | 25 | 1.18 (0.76 to 1.84) | 0.94 (0.56 to 1.57) | 13 | 0.78 (0.43 to 1.40) | 1.17 (0.61 to 2.24) | 33 | 1.26 (0.85 to 1.87) | 1.18 (0.75 to 1.87) |
Birth length ⩽10th percentile, n = 325 | 68 | 1.42 (1.06 to 1.91) | 1.07 (0.71 to 1.60) | 25 | 1.09 (0.70 to 1.70) | 0.58 (0.30 to 1.10) | 23 | 1.24 (0.78 to 1.97) | 0.90 (0.48 to 1.68) | 45 | 1.56 (1.10 to 2.22) | 1.09 (0.66 to 1.78) |
Birth length ⩾90th percentile, n = 414 | 48 | 0.70 (0.50 to 0.97) | 0.64 (0.44 to 0.92) | 35 | 1.07 (0.73 to 1.57) | 1.02 (0.66 to 1.56) | 12 | 0.45 (0.25 to 0.83) | 0.40 (0.21 to 0.77) | 36 | 0.88 (0.60 to 1.27) | 0.82 (0.54 to 1.24) |
BMI ⩽10th percentile, n = 279 | 50 | 1.19 (0.85 to 1.65) | 1.11 (0.78 to 1.58) | 23 | 1.17 (0.74 to 1.85) | 1.12 (0.69 to 1.82) | 22 | 1.39 (0.86 to 2.23) | 1.38 (0.84 to 2.25) | 28 | 1.09 (0.72 to 1.66) | 0.97 (0.62 to 1.52) |
BMI ⩾90th percentile, n = 273 | 44 | 1.04 (0.73 to 1.47) | 1.05 (0.72 to 1.51) | 28 | 1.46 (0.95 to 2.23) | 1.61 (1.04 to 2.51) | 10 | 0.65 (0.33 to 1.25) | 0.73 (0.37 to 1.43) | 34 | 1.36 (0.92 to 2.01) | 1.35 (0.89 to 2.04) |
BMI, body mass index at 4 years of age. The multivariate logistic regression models contained birth weight, birth length, BMI, family history of allergy, maternal age, sex, exclusive breastfeeding, presence of older siblings, gestational age, maternal smoking and socio-economic index.