Table 1 Cumulative incidence of both visual impairment and severe visual impairment and blindness per 10 000 live births*, Berkshire, Buckinghamshire, Oxfordshire and Northamptonshire, 1984–1998
Live births 1984–1988, n = 168 475Live births 1989–1993, n = 179 181Live births 1994–1998, n = 172 584p Trend‡
n (%)CI† (95% CI)n (%)CI† (95% CI)n (%)CI† (95% CI)
Severity
    VI¶131 (47.1)7.8 (6.5 to 9.2)135 (55.8)7.5 (6.3 to 8.9)102 (59.6)5.9 (4.8 to 7.2)0.04
    SVI/BL§147 (52.9)8.7 (7.4 to 10.3)107 (44.2)6.0 (4.9 to 7.2)69 (40.4)4.0 (3.1 to 5.1)<0.001
Gestational age
    ⩽28 weeks24 (8.6)640.0 (414.3 to 937.3)24 (9.9)361.4 (232.9 to 533.0)15 (8.8)182.5 (102.5 to 299.1)<0.001
    29–32 weeks22 (7.9)153.0 (96.1 to 230.7)19 (7.9)102.2 (61.6 to 159.1)7 (4.1)37.1 (14.9 to 76.2)0.001
    33–36 weeks33 (11.9)43.5 (30.0 to 61.1)26 (10.7)30.1 (19.7 to 44.0)24 (14.0)27.0 (17.3 to 40.1)0.07
    ⩾37 weeks199 (71.6)12.5 (10.9 to 14.4)173 (71.5)10.3 (8.8 to 11.9)125 (73.1)7.8 (6.5 to 9.4)<0.001
Birth weight**
    <1000 g16 (5.8)345.6 (198.8 to 555.1)18 (7.4)329.7 (196.5 to 516.0)7 (4.1)100.3 (40.4 to 205.5)0.004
    1000–1499 g23 (8.3)231.9 (147.5 to 345.9)16 (6.6)153.0 (87.7 to 247.2)12 (7.1)105.9 (54.8 to 184.3)0.02
    1500–1999 g21 (7.5)100.7 (62.5 to 153.5)17 (7.0)75.8 (44.2 to 121.0)12 (7.1)51.4 (26.6 to 89.6.0)0.06
    2000–2499 g29 (10.4)39.3 (26.3 to 56.4)33 (13.7)43.5 (29.7 to 61.3)13 (7.7)17.2 (9.2 to 29.4)0.02
    2500–3499 g126 (45.3)13.4 (11.2 to 16.0)93 (38.4)10.1 (8.1 to 12.4)80 (47.4)9.0 (7.2 to 11.2)0.004
    ⩾3500 g63 (22.7)10.0 (7.6 to 12.7)65 (26.9)9.3 (7.2 to 11.9)45 (26.6)6.4 (4.6 to 8.5)0.001
Sex
    Female124 (44.6)15.1 (12.6 to 18.0)84 (34.7)9.6 (7.7 to 11.9)68 (39.8)8.1 (6.3 to 10.2)<0.001
    Male154 (55.4)17.8 (15.1 to 20.9)158 (65.3)17.2 (14.6 to 20.0)103 (60.2)11.7 (9.5 to 14.1)0.001
Plurality
    Singletons264 (95.0)16.0 (14.1 to 18.1)236 (97.5)13.5 (11.8 to 15.4)156 (91.2)9.3 (7.9 to 10.9)<0.001
    Multiples14 (5.0)38.9 (21.3 to 65.3)6 (2.5)13.1 (4.8 to 28.6)15 (8.8)29.6 (16.6 to 48.8)0.54
Total278 (100.0)16.5 (14.6 to 18.6)242 (100.0)13.5 (11.9 to 15.3)171 (100.0)9.9 (8.5 to 11.5)<0.001
  • *Category specific denominators were used to calculated individual rates; †CI, cumulative incidence per 10 000 live births; ‡p value for the test for trend over time; ¶VI, visual impairment defined as a corrected visual acuity in the better eye of 6/18 to 6/60; §SVI/BL, severe visual impairment/blindness defined as a corrected visual acuity in the better eye of less than 6/60 or no useful vision; **birth weight was missing for 2 children born in 1994–1998.