Pertussis (ELISA) and polio (neutralisation) responses by group (Per Protocol population)
| Pediacel | DTwP-Hib+OPV | |||||
|---|---|---|---|---|---|---|
| DTwP-Hib, diphtheria–tetanus–whole-cell pertussis–Haemophilus influenzae type b; FHA, filamentous haemagglutinin; FIM, fimbrial agglutinins; GMT, geometric mean titres; OPV, oral poliomyelitis vaccine; PRN, pertactin; PT, pertussis toxin. | ||||||
| Values are mean (95% CI). | ||||||
| Pertussis | GMC (EU/ml), n = 105 | GMC (EU/ml), n = 102 | ||||
| PT | 78.7 (67.7 to 91.5) | 98.5 (77.6 to 125) | ||||
| FHA | 51.9 (45.2 to 59.7) | 25.7 (21.8 to 30.3) | ||||
| FIM | 278.7 (232.3 to 334.3) | 591.4 (479.1 to 730) | ||||
| PRN | 32.7 (26.3 to 40.6) | 68.9 (57.9 to 82) | ||||
| Poliomyelitis | n | GMT | ⩾1:8 (%) | n | GMT | ⩾1:8 (%) |
| Type 1 | 98 | 372 (270 to 514) | 100 (96.2 to 100) | 98 | 670 (456 to 983) | 100 (96.2 to 100) |
| Type 2 | 96 | 735 (510 to 1058) | 100 (96.2 to 100) | 98 | 2776 (2174 to 3545) | 100 (96.2 to 100) |
| Type 3 | 96 | 1077 (788 to 1472) | 97.9 (92.7 to 99.4) | 98 | 805 (579 to 1120) | 99 (94.4 to 99.8) |