Table 3

 Anti-polyribosylribitol phosphate (radioimmunoassay v ELISA) and MenC (serum bactericidal antibody) responses by group and stratum (Per Protocol population)

Anti-PRP (RIA)Anti-PRP (ELISA)Anti-MenC (SBA)
nGMC (μg/ml)⩾0.15 μg/ml (%)⩾1.0 μg/ml (%)nGMC (μg/ml)⩾0.15 μg/ml (%)⩾1.0 μg/ml (%)nGMT⩾1:8 (%)
DTwP-Hib, diphtheria–tetanus–whole–cell pertussis–Haemophilus influenzae type b; GMC, geometric mean concentration; GMT, geometric mean titre; MenC, meningococcal serogroup C; MCC-CRM, meningococcal group C conjugate with diphtheria-derived protein CRM197 as conjugate protein; MCC-TT, meningococcal group C conjugate with tetanus toxoid as conjugate protein; PRP, polyribosylribitol phosphate; RIA, radio immunoassay; SBA, serum bactericidal antibody.
Values are mean (95% CI).
Pediacel
    Overall1032.19 (1.58 to 3.03)93.2 (86.6 to 96.7)72.8 (63.5 to 80.5)1013.40 (2.47 to 4.66)91.1 (83.9 to 95.2)80.2 (71.4 to 86.8)1011216 (880 to 1680)99.0 (94.6 to 99.8)
    MCC-TT533.67 (2.56 to 5.26)98.1 (90.1 to 99.7)83 (70.8 to 90.8)525.17 (3.53 to 7.58)94.2 (84.4 to 98)90.4 (79.4 to 95.8)51690 (418 to 1140)98 (89.7 to 99.7)
    MCC-CRM501.26 (0.75 to 2.13)88 (76.2 to 94.4)62 (48.2 to 74.1)492.17 (1.34 to 3.53)87.8 (75.8 to 94.3)69.4 (55.5 to 80.5)502165 (1517 to 3089)100 (92.9 to 100)
DTwP-Hib
    Overall1023.18 (2.57 to 3.93)100 (96.4 to 100)82.4 (73.8 to 88.5)1005.7 (4.5 to 7.24)99 (94.6 to 99.8)90 (82.6 to 94.5)1013178 (2416 to 4180)100 (96.3 to 100)
    MCC-TT494.01 (2.97 to 5.42)100 (92.7 to 100)87.8 (75.8 to 94.3)497.51 (5.54 to 10.19)100 (92.7 to 100)91.8 (80.8 to 96.8)493816 (2583 to 5638)100 (92.7 to 100)
    MCC-CRM532.57 (1.91 to 3.45)100 (93.2 to 100)77.4 (64.5 to 86.5)514.38 (3.08 to 6.22)98 (89.7 to 99.7)88.2 (76.6 to 94.5)522674 (1807 to 3956)100 (93.1 to 100)