Summary of all infants with increased thyroid stimulating hormone level (>15 mU/l) who underwent dual scanning
| Sex | Guthrie TSH (days) | Ven TSH (days) | Ven T4 (days) | Age at Rx (days) | Ultrasound report | Isotope scanning | Diagnosis | Conc | |
|---|---|---|---|---|---|---|---|---|---|
| Report; TSH/age (days) | Day of Rx | ||||||||
| A, athyreosis; conc, concordance; D, dyshormonogenesis; E, ectopia; F, female; hemi, hemi-agenesis; hypo, hypoplasia; M, male; mat. abs, maternal blocking antibodies; NA, not applicable; prem, prematurity; Rx, start of thyroxine treatment; SU, status uncertain; T4, free thyroxine (pmol/l); TETSH, transient hyperthyrotropinaemia; TH, transient hypothyroidism; TSH, thyroid stimulating hormone; Ven, venous. | |||||||||
| The age at neonatal (Guthrie card) screening, venepuncture and Rx is given in days. Guthrie TSH is capillary TSH on neonatal screening. | |||||||||
| *Total thyroxine (nmol/l). | |||||||||
| The TSH on the day of isotope scan (or nearest available day) is shown. | |||||||||
| F | 173 (7) | 477 (13) | 7 (13) | 13 | No tissue | Faint uptake base of tongue; 5.8/27 | 15 | E | Yes |
| F | 152 (8) | 155.3 (16) | 10 (16) | 15 | No tissue | Small area base of tongue; NA/17 | 2 | E | Yes |
| M | 83 (5) | NA (11) | 79* (11) | 11 | Lingual thyroid | Uptake thyroid region;76.8/14 | 4 | E | Yes |
| F | 465 (8) | 464 (14) | 7.2 (14) | 14 | No tissue | Sublingual thyroid; 26/20 | 7 | E | Yes |
| F | 238 (7) | 514 (11) | 5.7 (11) | 11 | No tissue | Small area midline of tongue; NA/15 | 5 | E | Yes |
| F | 135 (7) | >100 (9) | 66 (9) | 9 | No tissue | Lingual uptake in midline; 70.8/15 | 7 | E | Yes |
| M | 78 (7) | 370 (12) | 9.2 (12) | 12 | No tissue | Small area post. to tongue; 13.2/17 | 6 | E | Yes |
| F | 165 (6) | >100 (9) | 26.7 (9) | 10 | No tissue | Lingual thyroid; NA/15 | 6 | E | Yes |
| F | 42 (5) | 22.6 (12) | 15.7 (12) | 58 | No tissue | Uptake higher, more post; NA/30 | 0 | E | Yes |
| M | 149 (7) | 354.5 (13) | 6.2 (13) | 13 | No tissue | Tiny area base of tongue;354 (13d)/14 | 2 | E | Yes |
| F | 41 (7) | 20.7 (10) | 16.3 (10) | 155 | No tissue | Small sublingual; NA/49 | 0 | E | Yes |
| F | 140 (5) | >100 (8) | 70* (8) | 8 | No tissue | Focal tracer base of tongue; NA/13 | 6 | E | Yes |
| F | 447 (6) | >150 (10) | 29* (10) | 10 | No tissue;cysts on left | No uptake; NA/17 | 8 | A | Yes |
| M | 246 (5) | 141.1 (11) | 5 (11) | 11 | No tissue | No uptake; NA/27 | 7 | A | Yes |
| M | 271 (5) | >100 (11) | 3.7 (11) | 11 | No tissue | No uptake: extravasation; NA/14 | 4 | A | Yes |
| F | 301 (5) | 660 (10) | 8 (10) | 10 | No tissue | No uptake; 59.5/15 | 6 | A | Yes |
| F | 285 (5) | >150 (9) | 4.1 (10) | 8 | No tissue | No uptake;49.7 (35 days)/17 | 10 | A | Yes |
| F | 159 (5) | >150 (10) | <20* (10) | 10 | No tissue | No uptake; 204/16 | 7 | A | Yes |
| M | 279 (5) | 561 (12) | <6 (12) | 12 | No tissue | No uptake; 44.6/20 | 9 | A | Yes |
| F | 146 (5) | >150 (11) | 3 (11) | 11 | No tissue | No uptake; 70.4/16 | 6 | A | Yes |
| F | 258 (6) | 616.9 (12) | 3.6 (12) | 11 | No tissue | No uptake; 7.1 (14.5 months)/15 months | 15mo | A | Yes |
| F | 221 (6) | >150 (13) | <20* (13) | 13 | No tissue | No uptake; 6.7 (22 days)/16 | 4 | A | Yes |
| F | 163 (5) | >150 (9) | 35* (9) | 9 | No tissue | No uptake; 2.8/23 | 15 | A | Yes |
| F | 27 (7) | 7.4 (16) | 18 (16) | None | Left hemi-agenesis | Slightly asymmetrical;7.3/8 months | 0 | L Hemi | Yes |
| F | 54 (7) | 55 (12) | 17 (12) | 15 | Right hemi-agenesis | Uptake but formless oval;NA/19 | 5 | R Hemi | Yes |
| F | 23 (9) | 16.2 (22) | 14 (22) | 207 | Rounded nodule | Rounded area of uptake;NA/5 months | 0 | Hypo | Yes |
| F | 255 (6) | >150 (8) | 84 (8) | 8 | Small | Faint uptake midline;11.7/15 | 8 | Hypo | Yes |
| F | 208 (7) | 72.3 (10) | 4.5 (10) | 12 | Large | Good uptake; NA/17 | 6 | D | Yes |
| F | 49 (7) | >100 (14) | 8 (14) | 14 | Large | Globally enlarged; 68.3/20 | 7 | D | Yes |
| M | 16 (4) | 14.8 (36) | 9 (36) | 0 | Large | Normal; NA/2 months | 0 | D | Yes |
| F | 300 (6) | >150 (11) | <20* (11) | 11 | Large | Normal; NA/17 | 7 | D | Yes |
| M | 29 (6) | 55 (10) | 11 (10) | 10 | Normal | Normal ; 5.3/17 | 8 | D | Yes |
| M | 41 (13) | 117.8 (21) | 6.6 (21) | 21 | Normal | Normal; 10.2/28 | 8 | TH (prem) | Yes |
| F | 27 (9) | 33.6 (31) | 92* (31) | None | Small | Normal; 24.4/47 | 0 | TETSH | Yes |
| F | 55 (5) | 77 (10) | 14.1 (10) | 10 | Right hemi-agenesis | No uptake; NA/16 | 7 | R Hemi | No |
| F | 104 (5) | >150 (10) | <5 (10) | 10 | Small | No uptake;71.9 (14 days)/16 | 7 | Hypo | No |
| F | 120 (5) | >100 (12) | 9 (12) | 12 | Small | No uptake; 1/19 | 8 | Hypo | No |
| F | 77 (5) | 68.4 (10) | 14.3 (10) | 10 | No right lobe;cysts on left | No uptake;7.7 (22 days)/21 | 12 | Hypo | No |
| M | 248 (5) | >150 (11) | 40 (11) | 11 | Normal size but hypoechoic | No uptake; 30.8/28 | 18 | TH (mat. abs) | No |
| M | 33 (5) | 11.87 (4) | 220* (4) | 13 | Normal | No uptake; 2.2/20 | 8 | SU | No |