Outcome measures in children with asthma and GORD treated with omeprazole and placebo
| Omeprazole (n = 18) | Placebo (n = 18) | p value | |
|---|---|---|---|
| Values expressed as changes from baseline (week 0) to end of treatment (week 12) with 95% confidence intervals for mean (±1.96 SEM) unless otherwise stated. | |||
| Symptom score | −1.28 (−2.65 to 0.1) | −1.28 (−3.27 to 0.72) | 1.00 |
| PAQLQ | −0.62 (−0.29 to −0.95) | −0.50 (−0.29 to −0.70) | 0.51 |
| FEV1% (mean, median) | −1.38 (0.33) | −2.01 (−0.50) | 0.77 |
| FEF25–75 (mean, median) | −0.07 (−0.05) | 0.04 (0.05) | 0.12 |
| Rescue medication (mean, median) | −1.9 (0.0) | −1.9 (0.5) | 0.89 |
| ECP baseline | 25.9 (14.3. 37.5) | 20.2 (12.7 to 27.7) | |
| ECP change | 1.27 (−5.5 to 8.1) | 1.39 (−4.3 to 7.1) | 0.98 |