Table 3

 Significance of a straight line regression of INH concentrations on age with a common slope for genotype

Time after INH dosing (hours)Ordinates at mean ageSlopep*
SSFSFF
SS, homozygous slow acetylators; FS, heterozygous fast acetylators; FF, homozygous fast acetylators.
*Significance of the slope coefficient.
28.6225.0783.8820.278<0.0005
36.6503.1282.0010.214<0.0005
45.1501.9241.0920.166<0.0005
54.0481.1290.6040.136<0.0005