Multiple regression analyses; effects of background variables, CH severity, and CH treatment variables on attention outcome*
| Cognitive reaction time (CalCAP)† | Freedom From Distractability | |||||||
|---|---|---|---|---|---|---|---|---|
| B | SE | β | p | B | SE | β | p | |
| *Background (SES, gender) and CH severity (serum T4 at diagnosis) included by forced entry (block 1) and CH treatment variables (starting dose, mean serum T4 levels) included by stepwise entry (block 2) in the regression analyses. We report unstandardised coefficients (B and standard error (SE)), standardised coefficients (β), and significance (p). | ||||||||
| †High scores on this test indicate more problems than low scores. | ||||||||
| SES | 1.09×10−2 | 0.01 | 0.16 | 0.28 | −1.49 | 1.32 | −0.16 | 0.26 |
| Gender (male = 1, female = 2) | 4.07×10−2 | 0.02 | 0.33 | 0.025 | 2.94 | 2.23 | 0.17 | 0.20 |
| Serum T4 at diagnosis | −1.38×10−4 | 0.00 | −0.06 | 0.66 | 0.10 | 0.04 | 0.34 | 0.013 |
| Thyroxine starting dose | 0.83 | 0.36 | 0.31 | 0.027 | ||||
| Mean serum T4 0–2.0 years | −6.58×10−4 | 0.00 | −0.36 | 0.015 | 0.10 | 0.04 | 0.39 | 0.004 |
| Mean serum T4 2.1–6 years | ||||||||
| R2 adjusted | 0.17 | 0.30 | ||||||
| Significance of model | F (4,39) = 3.15, p = 0.025 | F (5,38) = 4.66, p = 0.002 | ||||||