Group | Post-streptococcal autoimmune dyskinesia (n = 40) | Neurology controls (n = 100) | Uncomplicated streptococcal infection (n = 40) | Autoimmune controls (n = 50) |
---|---|---|---|---|
Positive ABGA Western immunoblotting defined as specific antibody reactivity to discrete basal ganglia antigens (positive binding to molecular weight antigens). | ||||
ABGA ELISA | ||||
Mean (95% CI) | 0.396 (0.341 to 0.451) | 0.229 (0.207 to 0.251) | 0.189 (0.171 to 0.207) | 0.251 (0.20 to 0.302) |
ABGA Western B | ||||
% positive | 92.5% | 4% | 2% | 10% |
Antigen binding | ||||
40 kDa | 47.5% | 1% | 0% | 4% |
45 kDa | 40% | 0% | 0% | 0% |
60 kDa | 42.5% | 1% | 2% | 2% |
80 kDa | 25% | 0% | 0% | 0% |
Other | 30, 35, 42, 62, 95 kDa | 42, 43, 95 kDa | 35 kDa | 35, 50 kDa |
p value | <0.0001 | <0.001 | <0.0001 |