Table 1

 Red cell and platelet disorders treated by SCT

DisorderIndications
MSD, matched sibling donor; MUD, matched unrelated donor.
Red cell disorders
Thalassaemia majorMSD: routine
MUD/cord donors: developmental or pilot studies undertaken in specialist units
Sickle cell diseaseMSD: when severe complications present
Congenital erythropoietic porphyria (CEP, Gunther’s disease)MSD/MUD/cord
Congenital dyserythropoietic anaemia (CDA) types I and IISeverely affected patients only
Hereditary sideroblastic anaemiaSeverely affected patients only
Pyruvate kinase deficiencySeverely affected patients only
Platelet disorders
Glanzmann’s thrombastheniaSeverely affected patients only