Table 1

 Classification of hereditary spherocytosis (modified from Eber et al3)

ClassificationMildModerateSevere
©1990, with permission from Elsevier.
Haemoglobin (g/l)110–15080–12060–80
Reticulocyte count (%)3–6>6>10
Bilirubin (μg/l)17–34>34>51
SplenectomyUsually not requiredIndicated during school age, usually before pubertyNecessary—delay until 6 years if possible