Table 1

Gentamicin dosing regimen and defined acceptable range for creatinine

Regimen	Age	Weight <2.0 kg	Weight ⩾2.0 kg
*On the eighth day of life it was recommended that dosage was stepped up where appropriate to the dose indicated for an 8 day old infant using the regime allocated at randomisation.
†All children in the once daily group received an initial dose of 8 mg/kg before continuing with routine dosing adjusted for weight and age.
Once daily†	⩽7 days*	2 mg/kg (group A.1)	4 mg/kg (group B.1)
Once daily†	>7 days	4 mg/kg (group C.1)	6 mg/kg (group D.1)
Multi-dose	⩽7 days*	2.5 mg/kg bd (group A.2)	2.5 mg/kg bd (group B.2)
Multi-dose	>7 days	2.5 mg/kg bd (group C.2)	2.5 mg/kg tds (group D.2)
Upper limit for creatinine μmol/l ^23, ²⁴
Age 0–2 days		190	140
Age 3–7 days		120	110
Age 8–14 days		100	90
Age 14+ days		90	90