Cardiac characteristics and outcomes of 17 children with enterovirus rhombencephalitis associated heart failure
| No. | Sex | Age (mth) | Virology | Max HR | Max SBP | CK | CKMB/CK | Electrocardiography | CXR C/T ratio | PO | Echocardiography | Outcome | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| QTc (ms) | Initial EF (%) | F-U EF (%) | Valvular regurgitation | ||||||||||||
| AR, aortic regurgitation; AV, atrioventricular; CK, creatine kinase; CKMB, muscle-brain fraction of creatine kinase; C/T, cardiothoracic; CXR, chest x ray; EF, ejection fraction of the left ventricle; EV, enterovirus; EV71, enterovirus 71; F, female; HR, heart rate; M, male; Max, maximum; Min, minimum; MR, mitral regurgitation; N, no; NA, not available; PO, pulmonary oedema; QTc, corrected QT interval; SBP, systolic blood pressure; SSS, sick sinus syndrome; TR, tricuspid regurgitation; VT, ventricular tachycardia; Y, yes. | |||||||||||||||
| *Pathological study of the heart. | |||||||||||||||
| 1 | M | 6 | EV | 216 | 122 | 103 | 1.9 | 400 | 0.53 | N | 46 | MR (2+) | Death* | ||
| 2 | M | 12 | EV | 250 | 116 | 406 | 9.1 | 378 | 0.39 | Y | 35 | MR (2+) | Death | ||
| 3 | M | 17 | EV | 207 | 116 | 251 | 1.6 | 454 | ST depression, T inversion | 0.50 | Y | 56 | 20 | MR (2+), TR (1+) | Death |
| 4 | F | 51 | EV | 190 | 120 | 321 | 12.1 | 446 | ST depression | 0.42 | Y | 25 | 17 | MR (2+), TR (1+) | Death |
| 5 | F | 7 | EV | 210 | 105 | 115 | 7.6 | 481 | 0.54 | Y | 30 | MR (2+), AR (1+) | Death | ||
| 6 | F | 8 | EV | 155 | 90 | 443 | 8.4 | 506 | 1st AV block, SSS, ST depression, T inversion | 0.53 | Y | 58 | MR (1+), TR (3+) | Death* | |
| 7 | F | 57 | EV71 | 180 | 119 | 454 | 19.4 | NA | NA | Y | NA | 18 | MR (2+), TR (1+) | Death | |
| 8 | M | 23 | EV | 160 | 105 | 31302 | 0.9 | 499 | T inversion | 0.56 | Y | 50 | MR (2+), TR (3+) | Death* | |
| 9 | F | 28 | EV71 | 240 | 165 | 47 | 25.5 | 416 | 0.55 | Y | 27 | 26 | MR (2+), TR (2+) | Death | |
| 10 | F | 14 | EV | 250 | 139 | 41 | 19.5 | 443 | VT | 0.45 | Y | 37 | MR (2+), TR (3+) | Death | |
| 11 | M | 20 | EV71 | 190 | 130 | 72 | 19.4 | 430 | 0.49 | Y | 27 | 27 | MR (2+), TR (1+) | Survival* | |
| 12 | F | 16 | EV71 | 235 | 156 | 510 | 6.7 | 401 | 0.49 | Y | 39 | 18 | MR (2+), TR (1+) | Survival | |
| 13 | M | 10 | EV71 | 243 | 112 | 111 | 37.8 | 449 | 0.52 | Y | 24 | 16 | MR (1+), TR (2+) | Death* | |
| 14 | F | 5 | EV71 | 198 | 119 | 369 | 25.2 | 341 | 0.53 | Y | 37 | MR (1+), TR (1+) | Survival | ||
| 15 | M | 4 | EV71 | 219 | 71 | 369 | 10.6 | 392 | 0.46 | Y | 40 | 28 | MR (2+), AR (1+) | Death* | |
| 16 | M | 9 | EV71 | 180 | 175 | 134 | 22.4 | 437 | ST depression | 0.51 | N | 46 | 34 | MR (2+), TR (1+) | Survival |
| 17 | M | 18 | EV71 | 197 | 136 | 132 | 19.7 | 356 | 0.49 | Y | 22 | MR (2+), TR (1+) | Death* | ||
| Mean | 18.7 | 207 | 123 | 2069 | 14.6 | 427 | 0.50 | 37 | 23 | ||||||
| SD | 16.8 | 30 | 26 | 7535 | 10.1 | 48 | 0.05 | 11 | 6 | ||||||
| Min | 4 | 155 | 71 | 41 | 0.9 | 341 | 0.39 | 22 | 16 | ||||||
| Max | 62 | 250 | 175 | 31302 | 37.8 | 506 | 0.56 | 58 | 34 | ||||||