Causes of bleeding in a well child
| Coagulation screen* or platelets | ||
|---|---|---|
| Normal | Abnormal | |
| ITP, idiopathic thrombocytopenic purpura; PAI-1, plasminogen activator inhibitor-1. | ||
| *Excluding von Willebrand factor. | ||
| Common | von Willebrand disease | ITP |
| Henoch-Schönlein purpura | Haemophilia A or B | |
| Vitamin K deficiency | ||
| Warfarin or heparin | ||
| Uncommon | Glanzmann’s thrombasthenia | Congenital platelet abnormality (excluding Glanzmann’s) |
| Platelet storage pool disorder | Deficiencies of factors II, V, VII, X, XI | |
| Factor XIII deficiency | Dysfibrinogenaemia | |
| PAI-1 deficiency | Afibrinogenaemia | |
| α2 antiplasmin deficiency | ||
| Ehlers-Danlos | ||
| Vitamin C deficiency | ||