Prolonged aPTT | von Willebrand disease* |
PT/fibrinogen/platelets normal | Factor VIII deficiency |
Factor IX deficiency |
| Factor XI deficiency |
| |
Prolonged PT | Warfarin ingestion |
aPTT/fibrinogen/platelets | Early vitamin K deficiency |
normal | Early liver dysfunction |
| Factor VII deficiency |
| |
Prolonged PT and aPTT | Over warfarinisation |
Fibrinogen/platelets normal | Severe vitamin K deficiency |
| Over heparinisation |
| Factor X, factor V, or prothrombin deficiency |
| Acquired inhibitors |
| |
Prolonged PT and aPTT | Severe liver dysfunction |
Decreased fibrinogen Normal or low platelets | Dysfibrinogenaemia/afibrinogenaemia |
| Disseminated intravascular coagulation (including meningococcal sepsis) |