Table 1

Group B streptococcal CPS–TT conjugate vaccines

GBS vaccineApproximate CPS dose (μg/ml)Proportion of adults with greater than fourfold rises in CPS specific IgG at 8 weeksGMC (μg/ml) of CPS specific IgG (95% CI) at 8 weeksEstimated percent of infant disease in the USA by GBS serotype†
*Data from reference 14 (Ia and Ib), 15 (II), and 16 and 17 (III). Unpublished observations for type V.
†Data from references 10 and 11.
Ia-TT*1580%18.3 (6.0 to 55.4)25
Ib-TT*1680%11.1 (3.3 to 37.0)5
II-TT*487%11.2 (6.1 to 20.8)5
III-TT*1393%2.7 (1.0 to 7.8)50
V-TT*1093%5.5 (1.5 to 20.0)15