Table 3

Multivariate relation between wheezing lower respiratory illness at 1 year of age (hospital, doctor, or clinic visits or hospital admission) and duration of predominant breast feeding

Wheezing lower respiratory tract illness*
Two or more hospital, doctor, or clinic visits n=290/2456Hospital admission n=84/2456
CrudeAdjusted†CrudeAdjusted†
Duration of predominant breast feedingOR (95% CI)p valueOR (95% CI)p valueOR (95% CI)p valueOR (95% CI)p value
*Wheezing lower respiratory tract illness, bronchiolitis, bronchospasm, or asthma.
†Independent effect of feeding exposure after adjustment for gender, gestational age, smoking in pregnancy, older siblings, maternal education, and maternal age. Each estimated odds ratio is adjusted for the effect of all other exposure variables. Values are odds ratios (95% confidence intervals) with p value following. For each level of exposure, the stated odds ratio contrasts the odds of illness (the illness category in the column headings compared with none) in individuals exposed at the time defined in column one compared with all later times.
Never/ever1.61 (1.13 to 2.29) 0.0091.61(1.05 to 2.48) 0.0291.67(0.91 to 3.07)0.0991.61(0.73 to 3.54)0.237
<2 mth/2 mth+1.70 (1.32 to 2.19)<0.00051.36(0.99 to 1.88) 0.0591.89(1.20 to 2.96)0.0061.66(0.92 to 3.01)0.092
<4 mth/4 mth+1.96 (1.49 to 2.56)<0.00051.70(1.25 to 2.30) 0.0012.48(1.48 to 4.20)0.0012.26(1.23 to 4.16)0.008
<6 mth/6 mth+1.67 (1.22 to 2.28) 0.0012.07(1.47 to 2.90)<0.00051.86(1.02 to 3.40)0.0422.65(1.30 to 5.41)0.007
<8 mth/8 mth+1.65 (1.18 to 2.32) 0.0041.61(1.08 to 2.40) 0.0181.74(0.91 to 3.32)0.0911.77(0.78 to 3.99)0.171