Length of stay, respiratory parameters, and antibiotic use in RSV patients with and without SIRS or bacterial co-infections
| Group 1 SIRS negative (no sepsis, no pneumonia) (n = 54) | Group 2 SIRS positive (no sepsis, no pneumonia) (n = 46) | Group 3 Bacterial pneumonia (no sepsis) (n = 24) | Group 4 Bacterial sepsis (no bacterial pneumonia) (n = 2) | Group 5 Bacterial sepsis and pneumonia (n = 1) | All patients (n = 127) | |
|---|---|---|---|---|---|---|
| NA, not applicable or no data; RSS, respiratory severity score (minimal score: 0, maximal score: 9). | ||||||
| *According to the study design, pneumonia was only diagnosed in intubated patients, thus leaving 100% of intubated patients in groups 3 and 5. | ||||||
| Results are given as median (range) or number (%). Some upper ranges for length of stay and ventilation are quite high, because a few patients were cared for and ventilated for other reasons after resolution of their RSV infection. | ||||||
| Community acquired bacterial pneumonia/sepsis | NA | NA | 12 (50%) | 1 (50%) | 1 (100%) | 14 (11%) |
| Length of hospital stay, days | 11 (1–158) | 9 (1–298) | 10 (1–168) | 12, 12 | 8 | 10 (1–298) |
| Length of ICU stay, days | 4 (0–76) | 3 (0–298) | 6 (1–62) | 9, 12 | 5 | 4 (0–298) |
| Mortality | 1 (1.9%) | 0 | 0 | 0 | 0 | 1 (0.8%) |
| Mechanical ventilation | 19 (36%) | 12 (26%) | 24 (100%)* | 1 | 1* (100%) | 57 (45%) |
| Intubation time, days | 5.5 (1–76) | 6.5 (0–298) | 4 (0–50) | 6 | 4 | 5 (0–298) |
| Nitric oxide | 7 (13%) | 3 (7%) | 2 (9%) | 1 | 0 | 13 (10%) |
| RSS on admission | 8 (3–9) | 8 (3–9) | 7 (6–9) | 8, NA | 9 | 8 (3–9) |
| RSS before intubation or CPAP | 8 (2–9) | 8.5 (5–9) | 7 (5–9) | NA | 9 | 8 (2–9) |
| Highest oxygenation index | 7.5 (1.4–28.6) | 5.0 (2.6–14.4) | 6.1 (1.7–14.4) | NA | NA | 6.0 (1.4–28.6) |
| Antibiotics | 29 (54%) | 31 (67%) | 23 (96%) | 2 (100%) | 1 (100%) | 86 (68%) |